The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2015
Filed:
May. 18, 2009
Christophe Blanchetot, Destelbergen, BE;
Martine Smit, Amsterdam, NL;
Regorius Leurs, Amsterdam, NL;
Sven Jähnichen, Amsterdamn, NL;
Michael John Scott Saunders, Brussels, BE;
Johannes Joseph Wilhelmus DE Haard, Oudelande, NL;
Peter Vanlandschoot, Bellem, BE;
Christophe Blanchetot, Destelbergen, BE;
Martine Smit, Amsterdam, NL;
Regorius Leurs, Amsterdam, NL;
Sven Jähnichen, Amsterdamn, NL;
Michael John Scott Saunders, Brussels, BE;
Johannes Joseph Wilhelmus De Haard, Oudelande, NL;
Peter Vanlandschoot, Bellem, BE;
Ablynx N.V., Zwijnaarde, BE;
Abstract
The present invention relates to amino acid sequences that are directed against (as defined herein) G-protein coupled receptors (GPCRs) and in particular to CXCR4 and CXCR7, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences (also referred to herein as 'amino acid sequences of the invention', 'compounds of the invention', and “polypeptides of the invention”, respectively). Furthermore, the invention provides a new method of making amino acid sequences that are directed against transmembrane protein, and in particular for multiple spanning transmembrane proteins for which the native conformation cannot be reproduced in other “in vitro” system (e.g. GPCRs in general).