The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2015
Filed:
Jul. 12, 2013
Applicants:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
The Brigham Women's Hospital, Inc., Boston, MA (US);
The University of Massachusetts, Boston, MA (US);
Inventors:
Elliot Androphy, Indianapolis, IN (US);
Gregory D. Cuny, Houston, TX (US);
Jonathan Cherry, Carmel, IN (US);
Marcie A. Glicksman, Winchester, MA (US);
Assignee:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/12 (2006.01); C12N 5/00 (2006.01); C07K 14/47 (2006.01); C07C 311/37 (2006.01); C07D 261/06 (2006.01); C07D 213/75 (2006.01); C07D 215/227 (2006.01); C07D 401/04 (2006.01); C07D 405/12 (2006.01); C07D 239/82 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 493/04 (2006.01); C07D 277/46 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07C 311/37 (2013.01); C07D 213/75 (2013.01); C07D 215/227 (2013.01); C07D 239/82 (2013.01); C07D 261/06 (2013.01); C07D 277/46 (2013.01); C07D 401/04 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 493/04 (2013.01); C07C 2101/08 (2013.01); C07C 2103/20 (2013.01);
Abstract
Disclosed herein are compositions and methods for treatment of spinal muscular atrophy (SMA). In certain embodiments, compounds are provided that increase full-length survival of motor neuron (SMN) protein production by an SMN2 gene.