The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2015

Filed:

Jan. 20, 2012
Applicants:

Anil Vasudevan, Union Grove, WI (US);

Thomas Dale Penning, Elmhurst, IL (US);

Huanming Chen, Irvine, CA (US);

BO Liang, Beijing, CN;

Shaohui Wang, Beijing, CN;

Fengchun Wu, Beijing, CN;

Yan Shen, Beijing, CN;

Cuihua Liu, Beijing, CN;

Zhenguang Zou, Beijing, CN;

Marina Pliushchev, Vernon Hills, IL (US);

Inventors:

Anil Vasudevan, Union Grove, WI (US);

Thomas Dale Penning, Elmhurst, IL (US);

Huanming Chen, Irvine, CA (US);

Bo Liang, Beijing, CN;

Shaohui Wang, Beijing, CN;

Fengchun Wu, Beijing, CN;

Yan Shen, Beijing, CN;

Cuihua Liu, Beijing, CN;

Zhenguang Zou, Beijing, CN;

Marina Pliushchev, Vernon Hills, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4353 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/4353 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

Compounds of formula (I) or pharmaceutical acceptable salts are provided, wherein X˜X, R˜R, A, B, Z and n are defined in the description. And compositions containing said compounds, and the uses for inhibitors of kinases such as ALK, and the uses for treating cancer thereof are provided.


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