The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2015
Filed:
Jun. 11, 2014
Amgen Inc., Thousand Oaks, CA (US);
Matthew Weiss, Boston, MA (US);
Alessandro Boezio, Somerville, MA (US);
Christiane Boezio, Somerville, MA (US);
John R. Butler, Somerville, MA (US);
Margaret Yuhua Chu-Moyer, Brookline, MA (US);
Erin F. Dimauro, Cambridge, MA (US);
Thomas Dineen, Somerville, MA (US);
Russell Graceffa, Hampton, NH (US);
Angel Guzman-Perez, Belmont, MA (US);
Hongbing Huang, Lexington, MA (US);
Charles Kreiman, Belmont, MA (US);
Daniel La, Brookline, MA (US);
Isaac E. Marx, Cambridge, MA (US);
Benjamin Charles Milgrim, Cambridge, MA (US);
Hanh Nho Nguyen, Arlington, MA (US);
Emily Peterson, Cambridge, MA (US);
Karina Romero, Arlington, MA (US);
Brian Sparling, Watertown, MA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention provides compounds of Formula I, and pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases associated with the activity of sodium channels such as pain disorders and itch. Also provided are pharmaceutical compositions containing compounds of the present invention.