The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2015

Filed:

Mar. 18, 2013
Applicant:

Revance Therapeutics, Inc., Newark, CA (US);

Inventors:

Michael D. Dake, Stanford, CA (US);

Jacob M. Waugh, San Francisco, CA (US);

Assignee:

Revance Therapeutics, Inc., Newark, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/385 (2006.01); A61K 39/08 (2006.01); A61K 45/00 (2006.01); A61K 39/02 (2006.01); A61K 31/74 (2006.01); A01N 59/16 (2006.01); A61K 33/32 (2006.01); A61K 9/00 (2006.01); A61K 38/48 (2006.01); A61K 47/34 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0014 (2013.01); A61K 38/4893 (2013.01); A61K 39/08 (2013.01); A61K 47/34 (2013.01); C12Y 304/24069 (2013.01); C07K 2319/10 (2013.01);
Abstract

A composition for topical application of a botulinum toxin (including botulinum toxin derivatives) comprises a botulinum toxin and a carrier comprising a polymeric backbone comprising a long-chain polypeptide or nonpeptidyl polymer having attached positively charged branching or 'efficiency' groups. The invention also relates to methods for reducing muscle paralysis and other conditions that may be treated with a botulinum toxin, particularly paralysis of subcutaneous, and most particularly, facial, muscles, by topically applying an effective amount of the botulinum toxin and carrier, in conjunction, to the subject's skin or epithelium. Kits for administration are also described.


Find Patent Forward Citations

Loading…