The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Sep. 29, 2009
John Moon Ching Luk, Mid Levels, HK;
Nikki Pui Yue Lee, Pokfulam, HK;
Lingxiao Liu, Shanghai, CN;
Ronnie Tung Ping Poon, Sai Wan Ho, HK;
Sheung Tat Fan, Mid levels, HK;
John Moon Ching Luk, Mid Levels, HK;
Nikki Pui Yue Lee, Pokfulam, HK;
Lingxiao Liu, Shanghai, CN;
Ronnie Tung Ping Poon, Sai Wan Ho, HK;
Sheung Tat Fan, Mid levels, HK;
The University of Hong Kong, Hong Kong, HK;
Abstract
Compositions and methods for diagnosing, treating and/or preventing cancers characterized by CDH17 overexpression based on the detection of CDH17 or the use of CDH17 as a target for therapeutic intervention or prophylactic intervention are provided. Methods for diagnosing and/or monitoring liver cancers using the expressing of CDH17 involve detecting and/or quantitating the CDH17 protein or encoding nucleic acids (DNA or RNA) in a biological sample such as urine from the subject. Methods for treating liver cancers using CDH17 as a target and of sensitizing cells with aberrant expression of CDH17 have also been developed. The methods include suppression or knockdown of the expression of CDH17 by administering an effective amount of a CDH17 inhibitor.