The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2015

Filed:

Dec. 19, 2013
Applicant:

Bonac Corporation, Fukuoka, JP;

Inventors:

Tadaaki Ohgi, Fukuoka, JP;

Hirotake Hayashi, Fukuoka, JP;

Hisao Shirohzu, Fukuoka, JP;

Tomohiro Hamasaki, Fukuoka, JP;

Akihiro Itoh, Fukuoka, JP;

Hiroshi Suzuki, Fukuoka, JP;

Assignee:

BONAC Corporation, Fukuoka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/63 (2006.01); A61K 31/7105 (2006.01); A61K 31/7125 (2006.01); C12N 15/11 (2006.01); C07F 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/7105 (2013.01); A61K 31/7125 (2013.01); C07F 9/22 (2013.01); C12N 15/111 (2013.01); C12N 15/1136 (2013.01); C12N 2310/14 (2013.01); C12N 2310/318 (2013.01); C12N 2330/30 (2013.01);
Abstract

Provided is a novel nucleic acid molecule that can be produced easily and efficiently and can inhibit the expression of a gene. The nucleic acid molecule is a single-stranded nucleic acid molecule including an expression inhibitory sequence that inhibits expression of a target gene. The single-stranded nucleic acid molecule includes: a region (X); a linker region (Lx); and a region (Xc). The linker region (Lx) is linked between the regions (Xc) and (Xc). The region (Xc) is complementary to the region (X). At least one of the regions (X) and (Xc) includes the expression inhibitory sequence. The linker region (Lx) has a non-nucleotide structure including at least one of a pyrrolidine skeleton and a piperidine skeleton. According to this single-stranded nucleic acid molecule, it is possible to inhibit the expression of the target gene.


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