The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Jan. 11, 2013
Applicant:
Xoma Technology Ltd., Berkeley, CA (US);
Inventors:
Linda Masat, Walnut Creek, CA (US);
Mary Haak-Frendscho, Newark, CA (US);
Arnold H. Horwitz, San Leandro, CA (US);
Gang Chen, San Diego, CA (US);
Marina Roell, Concord, CA (US);
Assignee:
XOMA (US) LLC, Berkeley, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/24 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); C07K 16/245 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01); Y10S 514/885 (2013.01);
Abstract
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.