The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Sep. 08, 2010
Applicants:
Oliver Seitz, Berlin, DE;
Lucas Bethge, Potsdam, DE;
Sven Hainke, Berlin, DE;
Inventors:
Assignee:
HUMBOLDT-UNIVERSITAT ZU BERLIN, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07H 19/04 (2006.01); C12Q 1/68 (2006.01); B01L 3/00 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
C07H 21/00 (2013.01); C12Q 1/6813 (2013.01); C12Q 1/6869 (2013.01); C12Q 2525/117 (2013.01);
Abstract
The present invention relates to forced intercalation probes (FIT-probes) comprising at least one nucleoside analog which comprises at least a fluorescent artificial nucleobase directly bound to a carbon of a modified sugar moiety wherein said modified sugar moiety is a carba-sugar or an amino acid nucleic acid (AANA). Thereby the nucleoside analog is incorporated into DNA or RNA in the place of a single native base.