The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2015

Filed:

Oct. 13, 2011
Applicants:

Adam Kraszewski, Poznan, PL;

Joanna Romanowska, Lubon, PL;

Michal Sobkowski, Poznan, PL;

Agnieszka Szymanska-michalak, Sroda Wlkp, PL;

Jacek Stawinski, Poznan, PL;

Jerzy Boryski, Poznan, PL;

Andrzej Lipniacki, Warsaw, PL;

Andrzej Piasek, Warsaw, PL;

Inventors:

Adam Kraszewski, Poznan, PL;

Joanna Romanowska, Lubon, PL;

Michal Sobkowski, Poznan, PL;

Agnieszka Szymanska-Michalak, Sroda Wlkp, PL;

Jacek Stawinski, Poznan, PL;

Jerzy Boryski, Poznan, PL;

Andrzej Lipniacki, Warsaw, PL;

Andrzej Piasek, Warsaw, PL;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 19/04 (2006.01); C07H 19/048 (2006.01); C07H 19/10 (2006.01); C07H 19/20 (2006.01); C07F 9/02 (2006.01); C07F 9/6561 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65616 (2013.01); C07F 9/65586 (2013.01); C07H 19/10 (2013.01); C07H 19/20 (2013.01);
Abstract

An exemplary emboidment is related to a pharmaceutical composition of the class of nucleotide analogues and antiviral pro-nucleotides useful in partial or complete inhibition of human immunodeficiency virus (HIV). An exemplary embodiment is expressed in the formula (XVI): where X stands for Nand B stands for thymidine-1-yl, or X stands for H and B stands for uracil-1-yl or adenin-1-yl or hypoxanthin-1-yl.A method of synthesis of the nucleotide analogue using a phosphorylating agent for synthesis of the nucleotide analogue is provided.


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