The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2015

Filed:

Apr. 16, 2014
Applicant:

Arrien Pharmaceuticals Llc, Somerset, NJ (US);

Inventors:

Hariprasad Vankayalapati, Draper, UT (US);

Venkatakrishnareddy Yerramreddy, Hyderabad, IN (US);

Paramareddy Gangireddy, Hyderabad, IN (US);

Rajendra P. Appalaneni, Saddle River, NJ (US);

Assignee:

ARRIEN PHARMACEUTICALS LLC, Salt Lake City, UT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to compounds described by Formula I: salts thereof, their synthesis, and their use as ITK and JAK3 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such disease associated with abnormal cell growth such as autoimmune, inflammation, rheumatoid arthritis, systemic lupus erythematosus, atherosclerosis, ulcerative colitis, psoriatic arthritis, psoriasis, Crohn's, metabolic and cancer diseases. The present invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions and processes for preparing the compounds of the invention.


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