The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Dec. 14, 2012
Applicant:
Bayer Intellectual Property Gmbh, Monheim, DE;
Inventors:
Dirk Brohm, Mettmann, DE;
Melanie Heroult, Berlin, DE;
Marie-Pierre Collin, Wuppertal, DE;
Walter Hübsch, Wuppertal, DE;
Mario Lobell, Wuppertal, DE;
Klemens Lustig, Wuppertal, DE;
Sylvia Grünewald, Berlin, DE;
Ulf Bömer, Glienicke, DE;
Assignee:
BAYER INTELLECTUAL PROPERTY GmbH, Monheim, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/53 (2006.01); A61K 31/5355 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/53 (2013.01); A61K 31/5355 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01);
Abstract
This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.