The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Nov. 08, 2013
Applicant:
Activesite Pharmaceuticals, Inc., San Francisco, CA (US);
Inventors:
Sukanto Sinha, San Francisco, CA (US);
Tamie Jo Chilcote, San Francisco, CA (US);
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/335 (2006.01); C07D 207/34 (2006.01); G01C 21/36 (2006.01); C07D 231/14 (2006.01); C07D 401/04 (2006.01); C07D 405/04 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
C07D 207/34 (2013.01); C07D 231/14 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01); C07D 417/04 (2013.01); G01C 21/3626 (2013.01); G01C 21/3658 (2013.01);
Abstract
The present invention provides prodrugs of compounds that inhibit the activity of plasma kallikrein (PK) and methods of preventing and treating plasma kallikrein dependent diseases or conditions, for example, diabetic macular edema, with the prodrugs having the formula: