The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Apr. 19, 2012
Solomon Langermann, Baltimore, MD (US);
Linda Liu, Clarksville, MD (US);
Shannon Marshall, Baltimore, MD (US);
Sheng Yao, Columbia, MD (US);
Solomon Langermann, Baltimore, MD (US);
Linda Liu, Clarksville, MD (US);
Shannon Marshall, Baltimore, MD (US);
Sheng Yao, Columbia, MD (US);
MedImmune, LLC, Gaithersburg, MD (US);
Abstract
The present invention relates to antibodies and their antigen-binding fragments and to other molecules that are capable of immunospecifically binding to B7-H1 or PD-1. In some embodiments such molecules are additionally capable of modulating the ability of B7-H1 or B7-DC to bind to PD-1 or are capable of affecting the signaling activity of the B7-H1 or PD-1. The invention additionally concerns the uses of such molecules in the diagnosis and treatment of cancer and other diseases.