The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2015

Filed:

Sep. 19, 2013
Applicant:

Healthpartners Research Foundation, Bloomington, MN (US);

Inventors:

Leah Ranae Bresin Hanson, II, Vadnais Heights, MN (US);

William H. Frey, White Bear Lake, MN (US);

Samuel Scott Panter, San Francisco, CA (US);

Assignee:

HealthPartners Research Foundation, Bloomington, MN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); A61K 38/30 (2006.01); A61K 45/06 (2006.01); A61K 31/16 (2006.01); A61K 9/00 (2006.01); A61K 31/165 (2006.01); A61K 31/195 (2006.01); A61K 38/18 (2006.01); A61K 38/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/16 (2013.01); A61K 9/0043 (2013.01); A61K 31/165 (2013.01); A61K 31/195 (2013.01); A61K 38/1841 (2013.01); A61K 38/2006 (2013.01); A61K 38/28 (2013.01); A61K 38/30 (2013.01); A61K 45/06 (2013.01);
Abstract

Methods and pharmaceutical compositions for treating neurodegeneration in patients diagnosed with Parkinson's Disease. Intranasal therapeutic agents, e.g., chelators, are administered to the upper third of the nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal systemic side effects. Therapeutic agents include those substances that interact with iron and/or copper such as metal chelators generally, including but not limited to iron chelators, copper chelators, and antioxidants. A particular example of such therapeutic agents is the iron chelator deferoxamine (DFO).


Find Patent Forward Citations

Loading…