The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Jun. 08, 2010
Applicants:
Thomas Bayer, Gottingen, DE;
Oliver Wirths, Friedland, DE;
Inventors:
Thomas Bayer, Gottingen, DE;
Oliver Wirths, Friedland, DE;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/00 (2006.01); G01N 33/00 (2006.01); A01K 67/027 (2006.01); C07K 14/47 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); A01K 67/0275 (2013.01); C07K 14/4711 (2013.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0312 (2013.01); C12N 15/8509 (2013.01);
Abstract
The present invention describes a novel transgenic mouse model for the common sporadic form of Alzheimer's disease. More particularly, the invention relates to a nucleotide sequence encoding Aβ 4-42 in functional linkage with at least a promoter, signal peptide sequence and a polyadenylation signal sequence, a cell and a transgenic non-human animal comprising said nucleotide sequence, and their respective use in screening methods.