The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Sep. 13, 2012
Applicants:
Julian Davies, La Jolla, CA (US);
Ling Liu, Carmel, IN (US);
Jirong LU, Carmel, IN (US);
Inventors:
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/573 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C07K 16/2863 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); G01N 2500/04 (2013.01);
Abstract
Provided is a monoclonal antibody, or antigen-binding fragment thereof, that binds to c-Met. Such antibodies, or antigen-binding fragments thereof, are useful in in vivo, ex vivo or in vitro immunochemical and other imaging methods for detecting cell surface c-Met receptor levels for diagnostic, prognostic and predictive purposes, and for optimizing therapeutic regimens in patients harboring tumors in which c-Met is implicated in pathogenesis.