The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2015

Filed:

Oct. 03, 2008
Applicants:

Hyongsok Soh, Santa Barbara, CA (US);

Xinhui Lou, Goleta, CA (US);

Eric Lagally, Vancouver, CA;

Inventors:

Hyongsok Soh, Santa Barbara, CA (US);

Xinhui Lou, Goleta, CA (US);

Eric Lagally, Vancouver, CA;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); B01L 3/00 (2006.01); C40B 70/00 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C40B 30/04 (2013.01); B01L 3/502761 (2013.01); C12N 15/1013 (2013.01); C40B 70/00 (2013.01); B01J 2219/005 (2013.01); B01J 2219/00563 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00725 (2013.01); B01J 2219/085 (2013.01); B01L 2200/0652 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0454 (2013.01); C12N 15/1034 (2013.01);
Abstract

The invention provides a method of screening a library of candidate agents by contacting the library with a target in a reaction mixture under a condition of high stringency, wherein the target includes a tag that responds to a controllable force applied to the tag, and passing the members of the library through a microfluidic device in a manner that exposes the library members to the controllable force, thereby displacing members of the library that are bound to the target relative to their unbound counterparts. Kits and systems for use with the methods of the invention are also provided.


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