The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2015

Filed:

Dec. 01, 2011
Applicants:

Donald Thomas, San Diego, CA (US);

Wei LI, Hangzhou, CN;

Ning KE, San Diego, CA (US);

Nan LI, San Diego, CA (US);

Adrian Papas, San Diego, CA (US);

Manfred Watzele, Weilheim, DE;

Alexander Seiler, Habach, DE;

Tianxing Wang, Hangzhou, CN;

Yama Abassi, San Diego, CA (US);

Xiaobo Wang, San Diego, AZ (US);

Inventors:

Donald Thomas, San Diego, CA (US);

Wei Li, Hangzhou, CN;

Ning Ke, San Diego, CA (US);

Nan Li, San Diego, CA (US);

Adrian Papas, San Diego, CA (US);

Manfred Watzele, Weilheim, DE;

Alexander Seiler, Habach, DE;

Tianxing Wang, Hangzhou, CN;

Yama Abassi, San Diego, CA (US);

Xiaobo Wang, San Diego, AZ (US);

Assignee:

ACEA Biosciences, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/12 (2006.01); C12Q 1/02 (2006.01); G01N 33/543 (2006.01); G01N 21/25 (2006.01); G01N 21/64 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
C12M 25/04 (2013.01); C12Q 1/02 (2013.01); G01N 33/54373 (2013.01); G01N 21/253 (2013.01); G01N 21/6452 (2013.01); G01N 33/48735 (2013.01);
Abstract

An insert device and co-culture device assembly incorporating the insert device, which includes an insert chamber with two fluid impermeable side walls that extend from a microporous bottom to an open top to form an inner cavity. The first side wall is shaped to form a convex arc that follows between about half of a circumference of the well and less than an entire circumference of the well. The second side wall joins ends of the first side wall and protrudes inward towards a center of the convex arc. A flange extends outward from or beneath the top and is notched to form a gap adjacent to the second side wall, which forms an access port allowing access to the lower chamber with a micropipette tip when the insert device is inserted into a well of a single or multi-well plate.


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