The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Nov. 30, 2010
Applicants:
Horacio Uri Saragovi, Montreal, CA;
Véronique Guillemard, Bourail, FR;
Neil Cashman, Vancouver, CA;
Inventors:
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); G01N 33/566 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2863 (2013.01); G01N 33/566 (2013.01); C07K 2317/34 (2013.01); C07K 2317/75 (2013.01); G01N 2333/475 (2013.01); G01N 2500/02 (2013.01);
Abstract
There are provided herein novel monoclonal antibodies that selectively bind and/or activate TrkC receptors, pharmaceutical compositions thereof and the use thereof for treating or preventing conditions which require activation of TrkC, such as amyotrophic lateral sclerosis and other neurodegenerative conditions and motor neuron diseases. The monoclonal antibodies are useful to screen for agents that share the same binding epitope on the TrkC receptor.