The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Feb. 04, 2015
Abbvie, Inc., North Chicago, IL (US);
Natarajan Ramasubramanyan, Westborough, MA (US);
Lihua Yang, Westborough, MA (US);
Matthew Omon Herigstad, Charlestown, MA (US);
Hong Yang, Worcester, MA (US);
Kartik Subramanian, Northborough, MA (US);
Xiaobei Zeng, Carolina, PR (US);
Diane D. Dong, Shrewsbury, MA (US);
Wen Chung Lim, Worcester, MA (US);
Kathreen A. Gifford, Marlborough, MA (US);
Zehra Kaymakcalan, Westborough, MA (US);
Christopher Chumsae, North Andover, MA (US);
AbbVie, Inc., North Chicago, IL (US);
Abstract
The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided.