The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Mar. 13, 2013
Applicant:
Mars, Incorporated, McLean, VA (US);
Inventors:
Michael Van Zandt, McLean, VA (US);
Gunnar Erik Jagdmann, Jr., McLean, VA (US);
Assignee:
Mars, Incorporated, McLean, VA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); A61K 31/69 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01);
Abstract
The inventive boronic acid analogs are potent inhibitors of Arginase I and II activity. These compounds are candidate therapeutics for treating a disease or disorder associated with an imbalance in the activity or concentration of cellular arginase I and arginase II enzymes. The invention also provides pharmaceutical compositions of the inventive compounds and methods for using the compositions for therapy.