The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Jun. 26, 2014
Daisuke Roland Saito, San Mateo, CA (US);
Daniel D. Long, San Francisco, CA (US);
Lan Jiang, Foster City, CA (US);
Bryan Frieman, La Jolla, CA (US);
Daisuke Roland Saito, San Mateo, CA (US);
Daniel D. Long, San Francisco, CA (US);
Lan Jiang, Foster City, CA (US);
Bryan Frieman, La Jolla, CA (US);
THERAVANCE BIOPHARMA R&D IP, LLC, South San Francisco, CA (US);
Abstract
The invention provides 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds of formula (I): wherein R, R, and m are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.