The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2015

Filed:

Aug. 27, 2012
Applicants:

Vince Yeh, San Diego, CA (US);

Xiaolin LI, Emeryville, CA (US);

Xiaodong Liu, San Diego, CA (US);

Jon Loren, San Diego, CA (US);

Valentina Molteni, San Diego, CA (US);

Juliet Nabakka, San Diego, CA (US);

Bao Nguyen, San Diego, CA (US);

Hank Michael James Petrassi, Cardiff, CA (US);

Inventors:

Vince Yeh, San Diego, CA (US);

Xiaolin Li, Emeryville, CA (US);

Xiaodong Liu, San Diego, CA (US);

Jon Loren, San Diego, CA (US);

Valentina Molteni, San Diego, CA (US);

Juliet Nabakka, San Diego, CA (US);

Bao Nguyen, San Diego, CA (US);

Hank Michael James Petrassi, Cardiff, CA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/02 (2006.01); C07D 401/10 (2006.01); A61K 31/437 (2006.01); A61K 31/4353 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.


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