The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Jun. 28, 2013
Universite Claude Bernard Lyon I, Villeurbanne Cedex, FR;
Institut National Des Sciences Appliquees DE Lyon, Villeurbanne Cedex, FR;
Centre National DE LA Recherche Scientifique, Paris Cedex, FR;
Cpe Lyon Fcr, Villeurbanne, FR;
Jean-Pierre Praly, Vourles, FR;
Kaiss Aouadi, Le Kef, TN;
Samy Cecioni, Oullins, FR;
Luc Denoroy, Villeurbanne, FR;
Sandrine Parrot, Villeurbanne, FR;
UNIVERSITE CLAUDE BERNARD LYON I, Villeurbanne, unknown;
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, Villeurbanne, unknown;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
CPE LYON FCR, Villeurbanne, FR;
Abstract
The present invention relates to novel pyrrolidine derivatives of formula (I): wherein R, R, R, R, Rand X are as defined in claim, optionally in a zwitterionic form, in the form of a pure optical isomer, or in the form of a mixture of optical isomers in any proportions, or in a form enriched with an optical isomer, as well as their pharmaceutically acceptable salts, solvates or hydrates, and pharmaceutical compositions containing such compounds. These compounds are notably useful for treating, in particular in human beings, epilepsy, ischemia, neurodegenerative diseases such as Parkinson's disease or Huntington's chorea, multiple sclerosis, Devic's disease, Alzheimer's disease, psychiatric diseases such as schizophrenia, depression, addiction, allodynia and hyperalgia.