The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2015

Filed:

Feb. 22, 2012
Applicants:

Dennis E. Hruby, Albany, OR (US);

Tove C. Bolken, Keizer, OR (US);

Sean M. Amberg, Corvallis, OR (US);

Dongcheng Dai, Corvallis, OR (US);

Inventors:

Dennis E. Hruby, Albany, OR (US);

Tove C. Bolken, Keizer, OR (US);

Sean M. Amberg, Corvallis, OR (US);

Dongcheng Dai, Corvallis, OR (US);

Assignee:

Kineta Four, LLC, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/16 (2006.01); A61K 31/34 (2006.01); C07C 251/86 (2006.01); C07C 243/36 (2006.01); C07D 333/24 (2006.01); A61K 31/165 (2006.01); C07C 251/76 (2006.01); C07C 251/82 (2006.01); C07D 209/40 (2006.01); C07D 307/68 (2006.01); C07D 333/22 (2006.01); C07D 333/38 (2006.01); A61K 31/343 (2006.01);
U.S. Cl.
CPC ...
C07C 251/86 (2013.01); A61K 31/165 (2013.01); C07C 243/36 (2013.01); C07C 251/76 (2013.01); C07C 251/82 (2013.01); C07D 209/40 (2013.01); C07D 307/68 (2013.01); C07D 333/22 (2013.01); C07D 333/24 (2013.01); C07D 333/38 (2013.01); A61K 31/343 (2013.01); C07C 2101/02 (2013.01); C07C 2101/14 (2013.01); C07C 2103/20 (2013.01);
Abstract

Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, and Pichinde), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).


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