The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Aug. 29, 2011
Applicants:
Songping D. Huang, Kent, OH (US);
Anatoly K. Khitrin, Kent, OH (US);
Vindya S. Perera, Kent, OH (US);
Murthi S. Kandanapitiye, Kent, OH (US);
Inventors:
Songping D. Huang, Kent, OH (US);
Anatoly K. Khitrin, Kent, OH (US);
Vindya S. Perera, Kent, OH (US);
Murthi S. Kandanapitiye, Kent, OH (US);
Assignee:
Kent State University, Kent, OH (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61K 49/18 (2006.01); A61K 49/08 (2006.01); A61K 33/32 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1851 (2013.01); A61K 49/08 (2013.01); A61K 49/1821 (2013.01); A61K 33/32 (2013.01);
Abstract
This invention discloses a synthetic procedure for preparing nanoparticulate materials of various metal cyanide compounds containing manganese(II) ions in the crystal lattice with the surfaces coated by a hydrophilic compound, and their use as MRI contrast agents with high sensitivity, long blood circulation half lives and low toxicity at low-field and high field MR scanners.