The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Jun. 13, 2013
Hoffmann-la Roche Inc., Nutley, NJ (US);
Philipp Hadwiger, Kulmbach, DE;
Torsten Hoffmann, Weil am Rhein, DE;
Kerstin Jahn-Hofmann, Neu-Isenburg, DE;
Eric A. Kitas, Aesch, CH;
David L. Lewis, Madison, WI (US);
Peter Mohr, Basel, CH;
Hans Martin Mueller, Weilheim, DE;
Guenther Ott, Bayreuth, DE;
Ingo Roehl, Memmelsdorf, DE;
David B. Rozema, Middleton, WI (US);
HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);
Abstract
The invention provides use of novel compounds for delivery of nucleic acids, and conjugates of these compounds with nucleic acids. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to said compounds and co-administered with a delivery polymer to achieve mRNA knock down in vivo are disclosed therein.