The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2015
Filed:
Mar. 01, 2010
Applicants:
Daniel E. Mccallus, Cambridge, MA (US);
Catherine Pachuk, Northborough, MA (US);
Baohua Gu, Malvern, PA (US);
Inventors:
Daniel E. McCallus, Cambridge, MA (US);
Catherine Pachuk, Northborough, MA (US);
Baohua Gu, Malvern, PA (US);
Assignee:
ALNYLAM PHARMACEUTICALS, INC., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); C12N 15/1131 (2013.01); C12N 2310/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/53 (2013.01);
Abstract
The invention relates to methods and compositions for modulating viral replication through double-stranded RNA-mediated gene silencing (RNAi), wherein the antiviral methods and compositions preferentially target opposite strand replication intermediates of single-stranded RNA viruses.