The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2015

Filed:

May. 17, 2013
Applicant:

Dh Technologies Development Pte. Ltd., Singapore, SG;

Inventors:

John L. Campbell, Milton, CA;

Thomas Covey, Richmond Hill, CA;

Yves LeBlanc, Newmarket, CA;

Bradley B. Schneider, Bradford, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B05B 5/025 (2006.01); G01N 30/02 (2006.01); H01J 49/00 (2006.01); F23D 11/22 (2006.01); H01J 49/16 (2006.01); G01N 27/62 (2006.01); H01J 49/04 (2006.01);
U.S. Cl.
CPC ...
H01J 49/165 (2013.01); G01N 27/622 (2013.01); H01J 49/0081 (2013.01); H01J 49/0431 (2013.01);
Abstract

An electrospray ion source method and system is provided for detecting emitter failure comprising a liquid chromatography column suitable for chromatographic separation of a sample. The column can have an inlet for receiving the sample; and an outlet for ejecting the sample. A make-up flow channel is provided for introducing make-up flow of liquid to the sample post-column, wherein the make-up flow normalizes the spray current. An electrospray ionization source is provided having one or more electrospray ionization emitter nozzles for receiving the make-up flow containing sample. A power supply can provide a voltage to the one or more emitter nozzles, and a measurement device can measure and monitor the spray current.


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