The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2015
Filed:
Mar. 15, 2010
Shinji Irie, Tokyo, JP;
Akira Tsujimura, Osaka, JP;
Yasushi Miyagawa, Osaka, JP;
Hiromitsu Tanaka, Sasebo, JP;
Shinji Irie, Tokyo, JP;
Akira Tsujimura, Osaka, JP;
Yasushi Miyagawa, Osaka, JP;
Hiromitsu Tanaka, Sasebo, JP;
TOPPAN PRINTING CO., LTD., Tokyo, JP;
OSAKA UNIVERSITY, Osaka, JP;
KYUSHU BUNKA GAKUEN SCHOOL FOUNDATION, Nagasaki, JP;
Abstract
An object of the present invention is to provide a test/diagnosis method for fertility which allows the estimation of the possibility of leading to pregnancy based on the ability of sperm to fuse with an egg and the identification of a cause of infertility; and a polynucleotide and a fertility testing kit which are used in the method. The present invention provides a test/diagnosis method for fertility, including a detection step of detecting on a biological sample taken from a human body, the presence or absence of a deletion or mutation in the human PGAM4 gene; a polynucleotide consisting of the base sequence of the human wild-type PGAM4 gene or the base sequence of the translation region of the gene, wherein the polynucleotide consists of a base sequence of 10-100 consecutive bases containing a mutated site of a single base substitution mutation having a high correlation with fertility; and a test kit for fertility comprising a reagent for detecting the presence or absence of a deletion or mutation in the human PGAM4 gene.