The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2015

Filed:

May. 15, 2013
Applicant:

Agilent Technologies, Inc., Loveland, CO (US);

Inventors:

Bo U. Curry, Redwood City, CA (US);

Jayati Ghosh, Cupertino, CA (US);

Brian Jon Peter, Los Altos, CA (US);

Arjun Vadapalli, Sunnyvale, CA (US);

Assignee:

Agilent Technologies, Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07H 21/00 (2006.01); G06F 19/18 (2011.01);
U.S. Cl.
CPC ...
C12Q 1/6827 (2013.01); C12Q 1/6883 (2013.01); G06F 19/18 (2013.01); C12Q 2600/158 (2013.01);
Abstract

A method for determining the ploidy of a test genome is provided. In some embodiments, the method may comprises: a) obtaining a plurality of ratios for polymorphisms that are distributed throughout a test genome, wherein each of the ratios is a ratio of the measured copy number of uncut allele in a polymorphic site relative to the measured copy number of the uncut allele in the reference sample; b) taking the log of the ratios and plotting a distribution of the reference corrected log ratios of the SNP probes; and c) determining the ploidy of said the genome based on the number of peaks in that distribution.


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