The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2015

Filed:

Feb. 14, 2012
Applicants:

Chun Zhang, Chongqing, CN;

Kai Fan, Chongqing, CN;

Xuefeng MA, Chongqing, CN;

LI Yang, Chongqing, CN;

Chunlan HU, Chongqing, CN;

Hua Luo, Chongqing, CN;

Xiang Mei, Chongqing, CN;

Inventors:

Chun Zhang, Chongqing, CN;

Kai Fan, Chongqing, CN;

Xuefeng Ma, Chongqing, CN;

Li Yang, Chongqing, CN;

Chunlan Hu, Chongqing, CN;

Hua Luo, Chongqing, CN;

Xiang Mei, Chongqing, CN;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 9/96 (2006.01); A61K 47/48 (2006.01); C12N 9/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/96 (2013.01); A61K 47/48215 (2013.01); C12N 9/0048 (2013.01); C12Y 107/03003 (2013.01); A61K 38/00 (2013.01);
Abstract

Provided are a PEGylated analogue protein of canine urate oxidase, preparation method and use thereof. The analogue protein of canine urate oxidase is a canine urate oxidase, or a chimeric protein comprising part of the amino acid sequence of a canine urate oxidase and part of the amino acid sequence of a human urate oxidase, or a mutant protein thereof. The PEGylated analogue protein of canine urate oxidase and pharmaceutical compositions thereof according to the present invention can be used for the prevention and/or treatment of hyperuricemia and chronic gout.


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