The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2015
Filed:
Sep. 13, 2011
Miriam Tendler, Rio de Janeiro, BR;
Celso Raul Romero Ramos, Rio de Janeiro, BR;
Andrew J. G. Simpson, New York, NY (US);
Miriam Tendler, Rio de Janeiro, BR;
Celso Raul Romero Ramos, Rio de Janeiro, BR;
Andrew J. G. Simpson, New York, NY (US);
ALVOS—CONSULTORIA, DESENVOLVIMENTO E COMERCIALIZAçÃO DE PRODUTOS BIOTECNOLÓGICOS S/A, Rio de Janeiro, BR;
FUNDAçÃO OSWALDO CRUZ, Rio de Janiero, BR;
Abstract
The production of recombinant proteins using a synthetic gene for increased expression of the protein inis disclosed. More specifically, disclosed is a process for producing a recombinant Sm14 protein of, by providing a synthetic gene for increased production of Sm14 protein, producing the gene and genetically manipulating thestrain with the gene in order to produce a vaccine effectively. Improved methods are also provided for producing and purifying this protein fromcells, which can be scaled for industrial production.