The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2015
Filed:
Jul. 29, 2015
Applicant:
Fondazione Telethon, Rome, IT;
Inventors:
Assignee:
FONDAZIONE TELETHON, Rome, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/63 (2006.01); A61K 38/00 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); A61K 38/00 (2013.01); C12N 15/63 (2013.01); C07K 14/435 (2013.01); C07K 14/4702 (2013.01);
Abstract
The invention refers to TFEB related molecules, as variants, mutants, truncated proteins, chimeras etc. that are constitutively localized in the nucleus of a eukaryote cell. Such molecules have a therapeutic applicability in all of disorders that need of an induction of the cell authophagic/lysosomal system, as lysosomal storage disorders, neurodegenerative diseases, hepatic diseases, muscle diseases and metabolic diseases.