The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2015
Filed:
Aug. 29, 2012
John Howard Hutchinson, San Diego, CA (US);
Leo Bleicher, San Diego, CA (US);
Nick Cosford, La Jolla, CA (US);
Robert John Ardecky, La Jolla, CA (US);
Jiwen Zou, La Jolla, CA (US);
John Howard Hutchinson, San Diego, CA (US);
Leo Bleicher, San Diego, CA (US);
Nick Cosford, La Jolla, CA (US);
Robert John Ardecky, La Jolla, CA (US);
Jiwen Zou, La Jolla, CA (US);
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE, La Jolla, CA (US);
Abstract
The present invention relates to novel benzodiazepinone compounds of Formulae (I) wherein R, R, R, R, R, R, R, and Rare as defined herein. The invention also relates to pharmaceutical compositions containing such compounds, methods of use of such compounds and compositions, and methods for preparing the compounds and compositions. The compounds are Group II metabotropic glutamate antagonists or allosteric modulators and are useful for the treatment of a variety of CNS disorders.