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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9192665 B1

PDFFull Text
Date of Patent:
Nov. 24, 2015

Filed:

Oct. 27, 2011

Means and methods for treating dlbcl

Applicants:

Gerhard Zugmaier, Munich, DE;

Dirk Nagorsen, Munich, DE;

Juergen Scheele, Munich, DE;

Inventors:

Gerhard Zugmaier, Munich, DE;

Dirk Nagorsen, Munich, DE;

Juergen Scheele, Munich, DE;

Assignee:

AMGEN RESEARCH (MUNICH) GMBH, Munich, DE;

Attorney:

Marshall, Gerstein & Borun LLP

Primary Examiner:

Misook Yu

Assistant Examiner:

Nelson B Moseley, II

Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); C07K 16/2803 (2013.01); C07K 16/2809 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01);
Abstract

The present invention provides means and methods for treating diffuse large B cell lymphoma (DLBCL). Specifically, a bispecific CD19×CD3 antibody which engages T cells via its CD3 binding portion and concomitantly binds to CD19 on the surface of in particular, lymphoma cells via its CD19 binding portion (i.e. a bispecific T cell engager, 'BiTE') is administered for use in the treatment of tumorous mass of lymophoreticular tissue and/or extranodal lymphoma caused by DLBCL in a patient.

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Zugmaier, Gerhard. (2015). Means and methods for treating dlbcl (U.S. Patent No. 9192665). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9192665

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