The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2015
Filed:
Aug. 04, 2009
Tarek M. Fahmy, New Haven, CT (US);
Eric D. Stern, New Haven, CT (US);
Mark A. Reed, Monroe, CT (US);
Aleksandar Vacic, New Haven, CT (US);
James F. Klemic, Falls Church, VA (US);
Tarek M. Fahmy, New Haven, CT (US);
Eric D. Stern, New Haven, CT (US);
Mark A. Reed, Monroe, CT (US);
Aleksandar Vacic, New Haven, CT (US);
James F. Klemic, Falls Church, VA (US);
Yale University, New Haven, CT (US);
Abstract
The present invention relates to a device and method for determining the presence of a specific compound in solution. The device includes a nanosensor having an electrically conducting pathway between at least a first and second contact. The device also includes a first receptor, suitable for binding a specific compound in the solution, attached to the nanosensor, and a second receptor also suitable for binding the specific compound while the specific compound is bound to the first receptor. The second receptor is attached to an enzyme added to the solution. When the solution having the second receptor is added to the device, and a second compound that is a substrate for the enzyme is subsequently added to the solution, a measured difference in an electrical property in the device before and after the application of the second compound is indicative of the presence of the specific compound in the solution.