The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2015
Filed:
Aug. 25, 2011
Martin Bader, Penzberg, DE;
Monika Baehner, Munich, DE;
Juergen Fingerle, Kandern, DE;
Ulrich Kohnert, Habach, DE;
Jean-luc Mary, Huningue, FR;
Silke Mohl, Basel, CH;
Martin Bader, Penzberg, DE;
Monika Baehner, Munich, DE;
Juergen Fingerle, Kandern, DE;
Ulrich Kohnert, Habach, DE;
Jean-Luc Mary, Huningue, FR;
Silke Mohl, Basel, CH;
Hoffman—La Roche Inc., Little Falls, NJ (US);
Abstract
A lipid particle comprising an apolipoprotein, a phosphatidylcholine and a lipid, such as a phospholipid, fatty acid or steroid lipid. In one embodiment the lipid particle comprises only one apolipoprotein. In one embodiment the lipid particle is consisting of one apolipoprotein, a phospholipid, a lipid, and a detergent. In one embodiment the lipid is a second phosphatidylcholine, wherein the first phosphatidylcholine and the second phosphatidylcholine differ in one or two fatty acid residues or fatty acid residue derivatives which are esterified to the glycerol backbone of the phosphatidylcholine. In one embodiment the apolipoprotein is selected from an apolipoprotein that has the amino acid sequence selected from SEQ ID NO: 01, 02, 06, 66, and 67, or is a variant thereof that has at least 70% sequence identity with the selected sequence.