The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2015
Filed:
Dec. 23, 2005
Janus Krarup, Gentofte, DK;
Thomas Budde Hansen, Copenhagen, DK;
Anne Charlotte Arentsen, Holte, DK;
Daniel E. Rasmussen, Copenhagen, DK;
Are Bogsnes, Nivå, DK;
Arne Staby, Bagsværd, DK;
Haleh Ahmadian, Solrød Strand, DK;
Susanne Bang, Bagsværd, DK;
Janus Krarup, Gentofte, DK;
Thomas Budde Hansen, Copenhagen, DK;
Anne Charlotte Arentsen, Holte, DK;
Daniel E. Rasmussen, Copenhagen, DK;
Are Bogsnes, Nivå, DK;
Arne Staby, Bagsværd, DK;
Haleh Ahmadian, Solrød Strand, DK;
Susanne Bang, Bagsværd, DK;
Novo Nordisk Healthcare A/G, Zurich, CH;
Abstract
The present invention relates to Vitamin K-dependent protein compositions having a very low, or negligible, content of protein contaminants. The present invention also relates to method applicable in the preparation of such Vitamin K-dependent protein compositions. Such methods may either be used alone or in sequential combination with the purpose of reducing the relative content of protein contaminants. The present invention is particularly relevant in the preparation of compositions of coagulation factors selected from Factor X polypeptides (FX/FXa), Factor IX polypeptides (FIX/FIXa), Factor VII polypeptides (FVII/FVIIa), and the anticoagulant Protein C, in particular Factor VII polypeptides.