The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2015

Filed:

Jan. 23, 2012
Applicants:

Steven M. Ruben, Brookeville, MD (US);

Steven C. Barash, Rockville, MD (US);

Gil H. Choi, Rockville, MD (US);

Tristan Vaughan, Cambridge, GB;

David Hilbert, Bethesda, MD (US);

Inventors:

Steven M. Ruben, Brookeville, MD (US);

Steven C. Barash, Rockville, MD (US);

Gil H. Choi, Rockville, MD (US);

Tristan Vaughan, Cambridge, GB;

David Hilbert, Bethesda, MD (US);

Assignee:

Human Genome Sciences, Inc., Wilmington, New Castle, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07K 14/705 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01); C07K 14/52 (2006.01); C07K 16/28 (2006.01); G01N 33/564 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70575 (2013.01); A61K 47/48561 (2013.01); A61K 49/0004 (2013.01); C07K 14/52 (2013.01); C07K 16/2875 (2013.01); G01N 33/564 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/622 (2013.01);
Abstract

The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.


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