The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2015

Filed:

Apr. 19, 2012
Applicants:

Damei Wang, Beijing, CN;

Wenjie LI, Beijing, CN;

Jinlei Zhang, Beijing, CN;

Inventors:

Damei Wang, Beijing, CN;

Wenjie Li, Beijing, CN;

Jinlei Zhang, Beijing, CN;

Assignee:

Gan & Lee Pharmaceuticals, Tongzhou District, Beijing, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/62 (2006.01); C07K 1/30 (2006.01); C30B 7/14 (2006.01); C30B 29/58 (2006.01);
U.S. Cl.
CPC ...
C07K 1/306 (2013.01); C07K 14/62 (2013.01); C30B 7/14 (2013.01); C30B 29/58 (2013.01);
Abstract

Disclosed is a method for preparing an insulin glargine (Gly-Arg-Ary-human insulin) crystal, comprising crystallizing the insulin glargine at pH 7.0-9.0 and in a crystallization solution containing a recombinant insulin glargine, an organic solvent of a 10-30% concentration by volume, a zinc compound, a phenol derivative, a salt and an organic acid.


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