The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2015

Filed:

May. 13, 2010
Applicants:

Ian G. Armitage, Stoneham, MA (US);

Reenu Chopra, Milton Road, GB;

Martin Ian Cooper, Foxton, GB;

Marianne Langston, North Andover, MA (US);

Steven P. Langston, North Andover, MA (US);

Stepan Vyskocil, Arlington, MA (US);

Inventors:

Ian G. Armitage, Stoneham, MA (US);

Reenu Chopra, Milton Road, GB;

Martin Ian Cooper, Foxton, GB;

Marianne Langston, North Andover, MA (US);

Steven P. Langston, North Andover, MA (US);

Stepan Vyskocil, Arlington, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 487/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

Disclosed is a compound of formula (I): crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula (I), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula (I), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.


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