The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2015
Filed:
Jun. 15, 2012
Carl Brooks, King of Prussia, PA (US);
Mui Cheung, King of Prussia, PA (US);
Hilary Schenck Eidam, King of Prussia, PA (US);
Krista B. Goodman, King of Prussia, PA (US);
Marlys Hammond, Littleton, CO (US);
Mark A. Hilfiker, King of Prussia, PA (US);
Tram H. Hoang, King of Prussia, PA (US);
Jaclyn R. Patterson, King of Prussia, PA (US);
Patrick Stoy, King of Prussia, PA (US);
Guosen YE, King of Prussia, PA (US);
Carl Brooks, King of Prussia, PA (US);
Mui Cheung, King of Prussia, PA (US);
Hilary Schenck Eidam, King of Prussia, PA (US);
Krista B. Goodman, King of Prussia, PA (US);
Marlys Hammond, Littleton, CO (US);
Mark A. Hilfiker, King of Prussia, PA (US);
Tram H. Hoang, King of Prussia, PA (US);
Jaclyn R. Patterson, King of Prussia, PA (US);
Patrick Stoy, King of Prussia, PA (US);
Guosen Ye, King of Prussia, PA (US);
GlaxoSmithKline Intellectual Property (No. 2) Limited, Brentford, Middlesex, GB;
Abstract
The present invention relates to spirocarbamate compounds of Formula (I) in which R1, (R2)Y, R3, R4, X and A have the meanings given in the specification. The invention further provides pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and relates to their use of these compounds as TRPV4 antagonists in treating or preventing conditions associated with TRPV4 imbalance.