The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2015

Filed:

Jun. 25, 2009
Applicants:

Natalie Dales, Cambridge, MA (US);

Zaihui Zhang, Burnaby, CA;

Jianmin Fu, Burnaby, CA;

Duanjie Hou, Burnaby, CA;

Shaoyi Sun, Burnaby, CA;

Vishnumurthy Kodumuru, Burnaby, CA;

Natalia Pokrovskaia, Burnaby, CA;

Inventors:

Natalie Dales, Cambridge, MA (US);

Zaihui Zhang, Burnaby, CA;

Jianmin Fu, Burnaby, CA;

Duanjie Hou, Burnaby, CA;

Shaoyi Sun, Burnaby, CA;

Vishnumurthy Kodumuru, Burnaby, CA;

Natalia Pokrovskaia, Burnaby, CA;

Assignees:

Novartis AG, Basel, CH;

Xenon Pharmaceuticals, Burnaby, BC, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/4439 (2006.01); C07D 213/81 (2006.01); A61K 31/444 (2006.01); C07D 401/04 (2006.01); C07D 409/12 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 213/81 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 409/12 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed.


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