The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2015

Filed:

Dec. 01, 2011
Applicants:

Xianhua Pan, Taizhou, CN;

Weijin LI, Taizhou, CN;

Qunhui Zhang, Taizhou, CN;

Libo Ruan, Taizhou, CN;

Wansheng Yu, Taizhou, CN;

Fei Deng, Taizhou, CN;

Tianhua MA, Taizhou, CN;

Mingwang Huang, Taizhou, CN;

Minhuan He, Taizhou, CN;

Inventors:

Xianhua Pan, Taizhou, CN;

Weijin Li, Taizhou, CN;

Qunhui Zhang, Taizhou, CN;

Libo Ruan, Taizhou, CN;

Wansheng Yu, Taizhou, CN;

Fei Deng, Taizhou, CN;

Tianhua Ma, Taizhou, CN;

Mingwang Huang, Taizhou, CN;

Minhuan He, Taizhou, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 211/34 (2006.01); C07C 323/25 (2006.01); C07C 209/62 (2006.01); C07D 203/08 (2006.01); C07D 203/10 (2006.01); C07D 203/24 (2006.01); C07D 487/04 (2006.01); C07C 271/22 (2006.01); C07C 319/20 (2006.01); C07F 7/10 (2006.01);
U.S. Cl.
CPC ...
C07C 323/25 (2013.01); C07C 209/62 (2013.01); C07C 271/22 (2013.01); C07C 319/20 (2013.01); C07D 203/08 (2013.01); C07D 203/10 (2013.01); C07D 203/24 (2013.01); C07D 487/04 (2013.01); C07F 7/10 (2013.01);
Abstract

Disclosed are intermediates of Sitagliptin, a preparation process thereof, and a process for synthesizing Sitagliptin using these intermediates. Sitagliptin is synthesized by using chiral amino compounds as a raw material, without having to build a chiral center with a chiral asymmetric catalytic hydrogenation, and high-pressure hydrogenation is avoided.


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