The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2015
Filed:
Apr. 04, 2011
Chang Hwan Kim, Suwon-si, KR;
Sung Kap Hong, Yongin-si, KR;
Byung Sun Lee, Seoul, KR;
Soo Young Kwak, Seoul, KR;
MI Ji Lee, Incheon, KR;
IN Young Choi, Yongin-si, KR;
SE Chang Kwon, Seoul, KR;
Chang Hwan Kim, Suwon-si, KR;
Sung Kap Hong, Yongin-si, KR;
Byung Sun Lee, Seoul, KR;
Soo Young Kwak, Seoul, KR;
Mi Ji Lee, Incheon, KR;
In Young Choi, Yongin-si, KR;
Se Chang Kwon, Seoul, KR;
HANMI SCIENCE CO., LTD, Hwaseong-si, KR;
Abstract
The present invention relates to a long-acting human follicle-stimulating hormone formulation having improved in vivo duration and stability, comprising a human follicle-stimulating hormone conjugate that is prepared by covalently linking human follicle-stimulating hormone with an immunoglobulin Fc region via a non-peptidyl polymer, and a preparation method thereof. The long-acting human follicle-stimulating hormone formulation of the present invention maintains in vivo activity of human follicle-stimulating hormone at a relatively high level and remarkably increases the serum half-life thereof.