The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2015

Filed:

Aug. 18, 2008
Applicants:

Michael J. Daly, Washington, DC (US);

Elena K. Gaidamakova, Gaithersburg, MD (US);

Vera Y. Matrosova, Rockville, MD (US);

Rodney L. Levine, Rockville, MD (US);

Nancy B. Wehr, Bethesda, MD (US);

Inventors:

Michael J. Daly, Washington, DC (US);

Elena K. Gaidamakova, Gaithersburg, MD (US);

Vera Y. Matrosova, Rockville, MD (US);

Rodney L. Levine, Rockville, MD (US);

Nancy B. Wehr, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/74 (2015.01); A61K 45/06 (2006.01); A61K 31/7076 (2006.01); A61K 33/32 (2006.01); A61K 8/24 (2006.01); A61K 8/44 (2006.01); A61K 8/60 (2006.01); A61Q 17/04 (2006.01); A61K 8/99 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 8/24 (2013.01); A61K 8/44 (2013.01); A61K 8/606 (2013.01); A61K 8/99 (2013.01); A61K 31/7076 (2013.01); A61K 33/32 (2013.01); A61K 35/74 (2013.01); A61Q 17/04 (2013.01);
Abstract

This invention encompasses methods of preserving protein function by contacting a protein with a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese). In addition, the invention encompasses methods of treating and/or preventing a side effect of radiation exposure and methods of preventing a side effect of radiotherapy comprising administration of a pharmaceutically effective amount of a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese) to a subject in need thereof. The compositions may compriseextracts.


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