The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2015
Filed:
Jan. 04, 2012
Applicants:
Che-kun James Shen, Taipei, TW;
Kuen-jer Tsai, Kaosiung, TW;
Inventors:
Che-Kun James Shen, Taipei, TW;
Kuen-Jer Tsai, Kaosiung, TW;
Assignee:
Academia Sinica, Taipei, TW;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4436 (2006.01); A61K 31/132 (2006.01); A61K 31/138 (2006.01); A61K 31/513 (2006.01); A61K 31/55 (2006.01); A61K 31/7016 (2006.01); A61K 31/4433 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4433 (2013.01); A61K 31/132 (2013.01); A61K 31/138 (2013.01); A61K 31/513 (2013.01); A61K 31/55 (2013.01); A61K 31/7016 (2013.01);
Abstract
Methods for rescuing learning, memory and/or motor function deficits associated with frontotemporal lobar degeneration with ubiquitinated inclusions (FTLD-U) are disclosed. The method comprises: a) administering to an animal having FTLD-U a therapeutically effective amount of an autophagy inducer; b) causing a decrease in the amount of ubiquitinated TDP-43 aggregation forms in the brain of the animal; and c) causing an improvement of the learning, memory capacities and/or motor function of the animal.