The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2015

Filed:

Aug. 14, 2013
Applicant:

Crescent Diagnostics Limited, London, GB;

Inventor:

Mark Robert Towler, Annacotty, IE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); G01J 3/44 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0075 (2013.01); A61B 5/0059 (2013.01); A61B 5/441 (2013.01); A61B 5/4504 (2013.01); A61B 5/4509 (2013.01); G01J 3/44 (2013.01);
Abstract

Methods of diagnosing bone disease such as osteoporosis are provided. The methods comprise detecting changes in the physical or chemical structure of a keratinized tissue as correlates of disease. The methods include detecting changes in the hardness, modulus, or level of sulfur bonding, particularly the level of disulfide bonding, in a keratinized tissue sample such as nail, hair, or skin. Changes in these variables serve as diagnostic markers of bone diseases that are associated with changes in bone elasticity and bone density.


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